Gillian McHugo

Computational biology
PhD researcher

University College Dublin

About

Computational biology PhD researcher at University College Dublin studying integrative genomics of infectious diseases in cattle, focusing on trypanosomiasis in hybrid African cattle and bovine tuberculosis in Irish cattle.

Education

PhD in Infection Biology, University College Dublin, 2018 - present

MSc in Evolutionary Biology, University College Dublin, 2015 - 2016
Thesis: A population genomic analysis of the endangered Galway sheep breed, published in Frontiers in Genetics.

BA (Mod) in Natural Sciences (Zoology), Trinity College Dublin, 2011 - 2015
Thesis: Mytilus edulis as a bioindicator of water pollution: Potential histopathology biomarkers in Dublin Bay and Newquay, Co. Clare.

Publications

All publications

Pamela A. Kelly, Gillian P. McHugo, Caitriona Scaife, Susan Peters, M. Lynn Stevenson, Jennifer S. McKay, David E. MacHugh, Irene Lara-Saez, Rory Breathnach (2024). Unveiling the role of endoplasmic reticulum stress pathways in canine demodicosis. Parasite Immunology, 46(4), e13033.

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James A. Ward, Said I. Ng’ang’a, Imtiaz A. S. Randhawa, Gillian P. McHugo, John F. O'Grady, Julio M. Flórez, John A. Browne, Ana M. Pérez O'Brien, Antonio J. Landaeta-Hernández, José F. Garcia, Tad S. Sonstegard, Laurent A. F. Frantz, Michael Salter-Townshend, David E. MacHugh (2024). Genomic insights into the population history and adaptive traits of Latin American Criollo cattle. Royal Society Open Science, 11(3), 231388.

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Thomas J. Hall, Gillian P. McHugo, Michael P. Mullen, James A. Ward, Kate E. Killick, John A. Browne, Stephen V. Gordon, David E. MacHugh (2023). Integrative and comparative genomic analyses of mammalian macrophage responses to intracellular mycobacterial pathogens. Tuberculosis, 102453.

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Sajad A. Bhat, Mahmoud Elnaggar, Thomas J. Hall, Gillian P. McHugo, Cian Reid, David E. MacHugh, Kieran G. Meade (2023). Preferential differential gene expression within the WC1.1⁺ γδ T cell compartment in cattle naturally infected with 𝘔𝘺𝘤𝘰𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘶𝘮 𝘣𝘰𝘷𝘪𝘴. Frontiers in Immunology, 14, 1265038.

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Carolina N. Correia, Gillian P. McHugo, John A. Browne, Kirsten E. McLoughlin, Nicolas C. Nalpas, David A. Magee, Adam O. Whelan, Bernardo Villarreal-Ramos, H. Martin Vordermeier, Eamonn Gormley, Stephen V. Gordon, David E. MacHugh (2022). High-resolution transcriptomics of bovine purified protein derivative-stimulated peripheral blood from cattle infected with 𝘔𝘺𝘤𝘰𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘶𝘮 𝘣𝘰𝘷𝘪𝘴 across an experimental time course. Tuberculosis, 136, 102235.

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James A. Ward, Gillian P. McHugo, Michael J. Dover, Thomas J. Hall, Said Ismael Ng’ang’a, Tad S. Sonstegard, Daniel G. Bradley, Laurent A.F. Frantz, Michael Salter-Townshend, David E. MacHugh (2022). Genome-wide local ancestry and evidence for mitonuclear coadaptation in African hybrid cattle populations. iScience, 25(7), 104672.

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Thomas J. Hall, Michael P. Mullen, Gillian P. McHugo, Kate E. Killick, Siobhán C. Ring, Donagh P. Berry, Carolina N. Correia, John A. Browne, Stephen V. Gordon, David E. MacHugh (2021). Integrative genomics of the mammalian alveolar macrophage response to intracellular mycobacteria. BMC Genomics, 22, 343.

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Gillian P. McHugo, Michael J. Dover, David E. MacHugh (2019). Unlocking the origins and biology of domestic animals using ancient DNA and paleogenomics. BMC Biology, 17, 98.

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Gillian P. McHugo, Sam Browett, Imtiaz A. S. Randhawa, Dawn J. Howard, Michael P. Mullen, Ian W. Richardson, Stephen D. E. Park, David A. Magee, Erik Scraggs, Michael J. Dover, Carolina N. Correia, James P. Hanrahan, David E. MacHugh (2019). A population genomics analysis of the native Irish Galway sheep breed. Frontiers in Genetics, 10, 927.

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Sam Browett, Gillian McHugo, Ian W. Richardson, David A. Magee, Stephen D. E. Park, Alan G. Fahey, John F. Kearney, Carolina N. Correia, Imtiaz A. S. Randhawa, David E. MacHugh (2018). Genomic characterisation of the indigenous Irish Kerry cattle breed. Frontiers in Genetics, 9, 51.

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Contact

gillianmchugo@pm.me

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