Bar charts showing the numbers of significantly differentially expressed genes for the different contrasts

Abstract

The extent of the bar above and below 0 on the vertical axis indicates the numbers of significantly differentially expressed genes (DEGs; B-H P_adj. ≤ 0.05) with increased and decreased expression, respectively. The position on the horizontal indicates the number of days post-infection (dpi) and the colour of the bars represents the tissue. The direct (DIRE) contrasts identify changes in expression in the N’Dama samples relative to the Boran samples (DIRE_i = N_i – B_i, where N represents the N’Dama population and B represents the Boran population), the N’Dama (NDAM) and Boran (BORA) contrasts identify changes in expression within the populations relative to time 0 (NDAM_i = N_i – N₀; BORA_i = B_i – B₀), and the response (RESP) contrasts identify changes in expression over time in the N’Dama samples relative to the Boran (RESP_i = [N_i – N₀] – [B_i – B₀]). The tissues include blood (BL), liver (LI), lymph node (LN), and spleen (SP) samples.